{"id":26057,"date":"2021-05-04T16:21:54","date_gmt":"2021-05-04T13:21:54","guid":{"rendered":"https:\/\/ramonfoundation.org.il\/?p=26057"},"modified":"2021-05-11T17:58:58","modified_gmt":"2021-05-11T14:58:58","slug":"%d7%90%d7%95%d7%a4%d7%98%d7%99%d7%a7%d7%94-%d7%a0%d7%99%d7%a1%d7%95%d7%99-%d7%94%d7%98%d7%9c%d7%a1%d7%a7%d7%95%d7%a4-%d7%94%d7%a0%d7%95%d7%96%d7%9c%d7%99-flute-2-2-2-2-2-2-2-4-2-4-2-2-3-2-2-2-2-2-2-39","status":"publish","type":"post","link":"https:\/\/ramonfoundation.org.il\/?p=26057","title":{"rendered":"spacetravel induced immune-dysfunction"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"26057\" class=\"elementor elementor-26057\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-bc002f0 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"bc002f0\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-183dc47\" data-id=\"183dc47\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f8bdd8b elementor-widget elementor-widget-text-editor\" data-id=\"f8bdd8b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><a style=\"color: white;\" href=\"https:\/\/ramonfoundation.org.il\/?p=25398\">HE<\/a> | <a style=\"color: white;\" href=\"https:\/\/ramonfoundation.org.il\/?p=29190\">\u0639\u0631\u0628\u064a\u0647<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-10dc07e\" data-id=\"10dc07e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ce927a4 elementor-nav-menu__align-center elementor-nav-menu__text-align-center elementor-nav-menu--dropdown-tablet elementor-nav-menu--toggle elementor-nav-menu--burger elementor-widget elementor-widget-nav-menu\" data-id=\"ce927a4\" data-element_type=\"widget\" data-settings=\"{&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i 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Team<\/a><\/li>\n<\/ul><\/nav>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-02028cb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"02028cb\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8f02008\" data-id=\"8f02008\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-64ff1b7 elementor-hidden-desktop elementor-widget elementor-widget-image\" data-id=\"64ff1b7\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"609\" height=\"606\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398.png 609w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398-300x300.png 300w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398-150x150.png 150w\" sizes=\"(max-width: 609px) 100vw, 609px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e997340 elementor-hidden-desktop elementor-widget elementor-widget-image\" data-id=\"e997340\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"241\" height=\"240\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png 241w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1-150x150.png 150w\" sizes=\"(max-width: 241px) 100vw, 241px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb08035 elementor-widget__width-inherit elementor-absolute elementor-widget elementor-widget-image\" data-id=\"eb08035\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"609\" height=\"606\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398.png 609w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398-300x300.png 300w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25398-150x150.png 150w\" sizes=\"(max-width: 609px) 100vw, 609px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-624bd0a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"624bd0a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-9f0bcab\" data-id=\"9f0bcab\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-357b04a elementor-widget elementor-widget-heading\" data-id=\"357b04a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">spacetravel induced immune-dysfunction<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e9c10a elementor-widget elementor-widget-heading\" data-id=\"3e9c10a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Sheba Medical Center<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bb8dc8a elementor-widget elementor-widget-heading\" data-id=\"bb8dc8a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Technion \u2013 Israel Institute of Technology\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e25af5f elementor-widget elementor-widget-heading\" data-id=\"e25af5f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Thomas Jefferson University, Philadelphia USA\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aecbe0f elementor-widget elementor-widget-heading\" data-id=\"aecbe0f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">OncoHost<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88607aa elementor-widget elementor-widget-heading\" data-id=\"88607aa\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Dr Yaacov Richard Lawrence<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-b084cd6 elementor-hidden-phone elementor-absolute elementor-widget elementor-widget-image\" data-id=\"b084cd6\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"241\" height=\"240\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png 241w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1-150x150.png 150w\" sizes=\"(max-width: 241px) 100vw, 241px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f026220 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f026220\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4457351\" data-id=\"4457351\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8f0d0c7 elementor-widget elementor-widget-text-editor\" data-id=\"8f0d0c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;A multidimensional analysis of spacetravel induced immune-dysfunction: implications for human health&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:5059,&quot;3&quot;:{&quot;1&quot;:0},&quot;4&quot;:{&quot;1&quot;:2,&quot;2&quot;:65280},&quot;9&quot;:1,&quot;10&quot;:1,&quot;11&quot;:4,&quot;12&quot;:0,&quot;15&quot;:&quot;arial, sans, sans-serif&quot;}\">A multidimensional analysis of spacetravel induced immune-dysfunction: implications for human health<\/span><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fb914b elementor-widget elementor-widget-text-editor\" data-id=\"8fb914b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;The majority of astronauts suffer immune dysfunction, as evident by latent virus reactivation and hypersensitivity reactions. This pilot study aims to demonstrate the feasibility of using a systems biology-based proteomics approach, including a commercial platform (Oncohost), to decipher the complexity of spaceflight-induced immune dysfunction. We will describe immune dysfunction pathophysiology that can be applied to both human diseases, and to the physiological responses seen when the body is exposed to extreme conditions. Such work will facilitate the stratification of immune dysfunction into appropriate molecular subtypes and facilitate the development of personalized therapies and interventions aiming to preserve \/ restore immune function.&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:5059,&quot;3&quot;:{&quot;1&quot;:0},&quot;4&quot;:{&quot;1&quot;:2,&quot;2&quot;:65280},&quot;9&quot;:0,&quot;10&quot;:1,&quot;11&quot;:4,&quot;12&quot;:0,&quot;15&quot;:&quot;arial, sans, sans-serif&quot;}\">The majority of astronauts suffer immune dysfunction, as evident by latent virus reactivation and hypersensitivity reactions. This pilot study aims to demonstrate the feasibility of using a systems biology-based proteomics approach, including a commercial platform (Oncohost), to decipher the complexity of spaceflight-induced immune dysfunction. We will describe immune dysfunction pathophysiology that can be applied to both human diseases, and to the physiological responses seen when the body is exposed to extreme conditions. Such work will facilitate the stratification of immune dysfunction into appropriate molecular subtypes and facilitate the development of personalized therapies and interventions aiming to preserve \/ restore immune function.<\/span><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b54d069 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"b54d069\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"mailto:yaacov.lawrence@sheba.health.gov.il\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">contact 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