{"id":26050,"date":"2021-05-04T16:21:23","date_gmt":"2021-05-04T13:21:23","guid":{"rendered":"https:\/\/ramonfoundation.org.il\/?p=26050"},"modified":"2021-05-11T17:31:21","modified_gmt":"2021-05-11T14:31:21","slug":"%d7%90%d7%95%d7%a4%d7%98%d7%99%d7%a7%d7%94-%d7%a0%d7%99%d7%a1%d7%95%d7%99-%d7%94%d7%98%d7%9c%d7%a1%d7%a7%d7%95%d7%a4-%d7%94%d7%a0%d7%95%d7%96%d7%9c%d7%99-flute-2-2-2-2-2-2-2-4-2-4-2-2-3-2-2-2-2-2-2-33","status":"publish","type":"post","link":"https:\/\/ramonfoundation.org.il\/?p=26050","title":{"rendered":"The effect of space conditions on the virulence of bacterial pathogens"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"26050\" class=\"elementor elementor-26050\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0c67756 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"0c67756\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e951e2f\" data-id=\"e951e2f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-05cebfc elementor-widget elementor-widget-text-editor\" data-id=\"05cebfc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><a style=\"color: white;\" href=\"https:\/\/ramonfoundation.org.il\/?p=25359\">HE<\/a> | <a style=\"color: white;\" href=\"https:\/\/ramonfoundation.org.il\/?p=29060\">\u0639\u0631\u0628\u064a\u0647<\/a><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2bec918\" data-id=\"2bec918\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-07351e5 elementor-nav-menu__align-center elementor-nav-menu__text-align-center elementor-nav-menu--dropdown-tablet elementor-nav-menu--toggle elementor-nav-menu--burger elementor-widget elementor-widget-nav-menu\" data-id=\"07351e5\" data-element_type=\"widget\" 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elementor-hidden-desktop elementor-widget elementor-widget-image\" data-id=\"64ff1b7\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"589\" height=\"467\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359.png 589w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359-300x238.png 300w\" sizes=\"(max-width: 589px) 100vw, 589px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e997340 elementor-hidden-desktop elementor-widget elementor-widget-image\" data-id=\"e997340\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"241\" height=\"240\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png 241w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1-150x150.png 150w\" sizes=\"(max-width: 241px) 100vw, 241px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb08035 elementor-widget__width-inherit elementor-absolute elementor-widget elementor-widget-image\" data-id=\"eb08035\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"589\" height=\"467\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359.png 589w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/25359-300x238.png 300w\" sizes=\"(max-width: 589px) 100vw, 589px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-228a5ea elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"228a5ea\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-98e347e\" data-id=\"98e347e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-357b04a elementor-widget elementor-widget-heading\" data-id=\"357b04a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The effect of space conditions on the virulence of bacterial pathogens<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e9c10a elementor-widget elementor-widget-heading\" data-id=\"3e9c10a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">the Infectious Diseases Research Laboratory, Sheba Medical Center, Tel-Hashomer<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88607aa elementor-widget elementor-widget-heading\" data-id=\"88607aa\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Prof. Ohad Gal-Mor\nHead, the Infectious Diseases Research Laboratory, \nSheba Medical Center, Tel-Hashomer\n<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-b084cd6 elementor-hidden-phone elementor-absolute elementor-widget elementor-widget-image\" data-id=\"b084cd6\" data-element_type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"241\" height=\"240\" src=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1.png 241w, https:\/\/ramonfoundation.org.il\/wp-content\/uploads\/2021\/05\/4-1-150x150.png 150w\" sizes=\"(max-width: 241px) 100vw, 241px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f026220 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f026220\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4457351\" data-id=\"4457351\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8f0d0c7 elementor-widget elementor-widget-text-editor\" data-id=\"8f0d0c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;The effect of space conditions on the expression of virulence pathways in the common human pathogen Salmonella enterica&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:5059,&quot;3&quot;:{&quot;1&quot;:0},&quot;4&quot;:{&quot;1&quot;:2,&quot;2&quot;:65280},&quot;9&quot;:1,&quot;10&quot;:1,&quot;11&quot;:4,&quot;12&quot;:0,&quot;15&quot;:&quot;arial, sans, sans-serif&quot;}\" data-sheets-textstyleruns=\"{&quot;1&quot;:0}\uee10{&quot;1&quot;:100,&quot;2&quot;:{&quot;6&quot;:1}}\">The effect of space conditions on the expression of virulence pathways in the common human pathogen Salmonella enterica<\/span><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fb914b elementor-widget elementor-widget-text-editor\" data-id=\"8fb914b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;The bacterial pathogen Salmonella enterica (S. enterica) is a leading cause of foodborne diseases and a common source of human and animal infections. Previous studies have shown that growing bacteria at the outer space significantly enhances their virulence, however the underlying mechanisms remains unknown. Here, we propose to use the AX1 mission and grow S. enterica cultures in space. Besides following the kinetic of bacterial growth under microgravity conditions, we aim to stabilize their RNA and determine their entire transcriptome using cutting-edge RNA-sequencing techniques. Comparison between the growth rate and the expression of all Salmonella genes between space and ground synchronically grown cultures will provide advanced understanding about the effect of space on Salmonella growth and its global gene expression.&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:13059,&quot;3&quot;:{&quot;1&quot;:0},&quot;4&quot;:{&quot;1&quot;:2,&quot;2&quot;:65280},&quot;11&quot;:4,&quot;12&quot;:0,&quot;15&quot;:&quot;Times&quot;,&quot;16&quot;:11}\">The bacterial pathogen Salmonella enterica (S. enterica) is a leading cause of foodborne diseases and a common source of human and animal infections. Previous studies have shown that growing bacteria at the outer space significantly enhances their virulence, however the underlying mechanisms remains unknown. Here, we propose to use the AX1 mission and grow S. enterica cultures in space. Besides following the kinetic of bacterial growth under microgravity conditions, we aim to stabilize their RNA and determine their entire transcriptome using cutting-edge RNA-sequencing techniques. Comparison between the growth rate and the expression of all Salmonella genes between space and ground synchronically grown cultures will provide advanced understanding about the effect of space on Salmonella growth and its global gene expression.<\/span><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b54d069 elementor-align-center elementor-widget__width-initial elementor-widget elementor-widget-button\" data-id=\"b54d069\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"mailto:Ohad.Gal-Mor@sheba.health.gov.il\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">contact 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